Find the Signal !
We Specialize in Bridging Preclinical Discovery With
Early Stage Clinical Development
What We Do:
- Selection of preclinical models that reflect the current clinical landscape.
- Determination of the mechanism of action & discovery of candidate biomarkers.
- Identification of lead compounds with the highest probability of clinical success.
- Differentiation from standard of care and competitors for optimal clinical positioning.
- Precision Medicine Approach to leverage disease heterogeneity and microenvironment.
- Design of clinical assays to confirm target engagement & mechanism of action in patients.
- Confirmation of biomarkers for patient stratification and late-phase clinical trial design.
Indications We Specialize In:
▶ Oncology
- Solid Tumors and Hematological Cancers
- Selection of Indication & Relevant Preclinical Models
- Target Engagement (Whole Blood & Paired Biopsies)
▶ Cardiometabolic Diseases
- Differentiation from latest therapies (triple G agonists, SGLT2 inhibitors).
- Contribution of microenvironment to disease pathology.
- Clinical design and endpoints.
▶ Fibrosis
- Molecular Hallmarks of lung, heart, kidney & liver inflammation & fibrosis.
- Tailored ex-vivo assays.
- Circulating biomarkers (preclinical & clinical).
